Abstract
Cellulose and its derivatives are widely used as nanofibrous biomaterials, but obtaining 3D cellulose nanofibers is difficult and relevant research is scarce. In the present study, we propose a simple method for converting electrospun 3D cellulose acetate/lactic acid nanofibers via calcium hydroxide treatment into a 3D cellulose/calcium lactate nanocomposite matrix. The conversion resulted in producing a stronger nanofibrous matrix (1.382 MPa vs. 0.112 MPa) that is more hydrophilic and cell-friendly compared to the untreated cellulose acetate/lactic acid group. The successful conversion was verified via FTIR, XPS, TGA, DTG, and XRD. The ability of the scaffolds to provide a suitable environment for cell growth and infiltration was verified by CCK assay and confocal microscopy. The porous nature, mechanical strength, and presence of calcium make the 3D cellulose/calcium lactate matrix a promising material for bone tissue engineering.
| Original language | English |
|---|---|
| Article number | 117191 |
| Journal | Carbohydrate Polymers |
| Volume | 253 |
| DOIs | |
| State | Published - 2021.02.1 |
Keywords
- 3D nanofibers
- Calcium lactate
- Cellulose
- Cellulose acetate
- Electrospinning
Quacquarelli Symonds(QS) Subject Topics
- Materials Science
- Engineering - Petroleum
- Chemistry
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