Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines

Yunjung Choi; Chang Hun Lee; Kyoung Min Kim; Wan Hee Yoo

doi:10.3390/vaccines10060923

Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines

Yunjung Choi
, Chang Hun Lee
, Kyoung Min Kim
, Wan Hee Yoo^*

^*Corresponding author for this work

Department of Medicine

Research output: Contribution to journal › Journal article › peer-review

7 Scopus citations

Abstract

IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephri-tis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they received either the ChAdOx1 viral vector (Oxford/AstraZeneca) vaccine or the messenger RNA-1273 (Moderna) vaccine. These cases suggest that COVID-19 vaccines have the potential to trigger IgA vasculitis and indicate that physicians need to monitor for this possible complication.

Original language	English
Article number	923
Journal	Vaccines
Volume	10
Issue number	6
DOIs	https://doi.org/10.3390/vaccines10060923
State	Published - 2022.06

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

ChAdOx1
COVID-19
IgA vasculitis
mRNA-1273
vaccination

Quacquarelli Symonds(QS) Subject Topics

Medicine
Pharmacy & Pharmacology
Biological Sciences

Access to Document

10.3390/vaccines10060923

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@article{f11b6c289bb34529a5584610d4813940,

title = "Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines",

abstract = "IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephri-tis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they received either the ChAdOx1 viral vector (Oxford/AstraZeneca) vaccine or the messenger RNA-1273 (Moderna) vaccine. These cases suggest that COVID-19 vaccines have the potential to trigger IgA vasculitis and indicate that physicians need to monitor for this possible complication.",

keywords = "ChAdOx1, COVID-19, IgA vasculitis, mRNA-1273, vaccination",

author = "Yunjung Choi and Lee, \{Chang Hun\} and Kim, \{Kyoung Min\} and Yoo, \{Wan Hee\}",

note = "Publisher Copyright: {\textcopyright} 2022 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2022",

month = jun,

doi = "10.3390/vaccines10060923",

language = "English",

volume = "10",

journal = "Vaccines",

issn = "2076-393X",

number = "6",

}

TY - JOUR

T1 - Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines

AU - Choi, Yunjung

AU - Lee, Chang Hun

AU - Kim, Kyoung Min

AU - Yoo, Wan Hee

PY - 2022/6

Y1 - 2022/6

N2 - IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephri-tis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they received either the ChAdOx1 viral vector (Oxford/AstraZeneca) vaccine or the messenger RNA-1273 (Moderna) vaccine. These cases suggest that COVID-19 vaccines have the potential to trigger IgA vasculitis and indicate that physicians need to monitor for this possible complication.

AB - IgA vasculitis is an immune complex-mediated small-vessel vasculitis that mainly occurs in children and is characterized by palpable purpura, arthralgia, abdominal pain, and glomerulonephri-tis. We report three cases of new-onset IgA vasculitis involving major organs in adult patients after they received either the ChAdOx1 viral vector (Oxford/AstraZeneca) vaccine or the messenger RNA-1273 (Moderna) vaccine. These cases suggest that COVID-19 vaccines have the potential to trigger IgA vasculitis and indicate that physicians need to monitor for this possible complication.

KW - ChAdOx1

KW - COVID-19

KW - IgA vasculitis

KW - mRNA-1273

KW - vaccination

UR - https://www.scopus.com/pages/publications/85132124485

U2 - 10.3390/vaccines10060923

DO - 10.3390/vaccines10060923

M3 - Journal article

AN - SCOPUS:85132124485

SN - 2076-393X

VL - 10

JO - Vaccines

JF - Vaccines

IS - 6

M1 - 923

ER -

Sudden Onset of IgA Vasculitis Affecting Vital Organs in Adult Patients following SARS-CoV-2 Vaccines

Abstract

UN SDGs

Keywords

Quacquarelli Symonds(QS) Subject Topics

Access to Document

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