Synthesis of functionalized polysuccinimide as a drug carrier

  • N. H. Lim*
  • , K. S. Seo
  • , S. Y. Jeung
  • , M. S. Kim
  • , S. H. Cho
  • , G. Khang
  • , H. B. Lee
  • *Corresponding author for this work

Research output: Contribution to conferenceConference paperpeer-review

Abstract

The synthesis of polyaspartamide having several functional groups such as polyethylene glycol (PEG) and phospholipids through ring opening of polysuccinimide (PSI) was discussed. PSI as the formation of nanoparticle micelle and the possibility as a drug carrier was also examined. The ring of PSI remained in PEG functionalized polyaspartamide and was also modified by the successive reaction with amine-functionalized phospholipids. The results show that the functionalized polyaspartamide formed nanoparticle micelle where the size ranged from 300 to 700 nm.

Original languageEnglish
Title of host publicationTransactions - 7th World Biomaterials Congress
Pages1180
Number of pages1
StatePublished - 2004
EventTransactions - 7th World Biomaterials Congress - Sydney, Australia
Duration: 2004.05.172004.05.21

Publication series

NameTransactions - 7th World Biomaterials Congress

Conference

ConferenceTransactions - 7th World Biomaterials Congress
Country/TerritoryAustralia
CitySydney
Period04.05.1704.05.21

Quacquarelli Symonds(QS) Subject Topics

  • Engineering & Technology

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