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T cell responses to SARS-CoV-2 in humans and animals

  • Sameer ul Salam Mattoo
  • , Jinjong Myoung*
  • *Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

SARS-CoV-2, the causative agent of COVID-19, first emerged in 2019. Antibody responses against SARS-CoV-2 have been given a lot of attention. However, the armamentarium of humoral and T cells may have differing roles in different viral infections. Though the exact role of T cells in COVID-19 remains to be elucidated, prior experience with human coronavirus has revealed an essential role of T cells in the outcomes of viral infections. Moreover, an increasing body of evidence suggests that T cells might be effective against SARS-CoV-2. This review summarizes the role of T cells in mouse CoV, human pathogenic respiratory CoV in general and SARS-CoV-2 in specific.

Original languageEnglish
Pages (from-to)276-289
Number of pages14
JournalJournal of Microbiology
Volume60
Issue number3
DOIs
StatePublished - 2022.03

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • coronavirus
  • immune response
  • SARS-CoV-2
  • T cell

Quacquarelli Symonds(QS) Subject Topics

  • Biological Sciences

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