Tetrabutylammonium tetra(tert-butyl alcohol)-coordinated fluoride as a facile fluoride source

Dong Wook Kim; Hwan Jeong Jeong; Seok Tae Lim; Myung Hee Sohn

doi:10.1002/anie.200803150

Tetrabutylammonium tetra(tert-butyl alcohol)-coordinated fluoride as a facile fluoride source

Dong Wook Kim
, Hwan Jeong Jeong
, Seok Tae Lim
, Myung Hee Sohn

Department of Medicine

Jeonbuk National University

Research output: Contribution to journal › Journal article › peer-review

152 Scopus citations

Abstract

(Figure Presented) F^- on: The title compound TBAF(tBuOH) ₄ can act as a highly effective fluoride source for nucleophilic fluorination thanks to its favorable properties, such as a stable structure (in which the fluoride ion is surrounded by four bulky nonpolar protic alcohol molecules), a dehydrated state, low hygroscopicity, good solubility in organic solvents, good nucleophilicity, and low basicity.

Original language	English
Pages (from-to)	8404-8406
Number of pages	3
Journal	Angewandte Chemie - International Edition
Volume	47
Issue number	44
DOIs	https://doi.org/10.1002/anie.200803150
State	Published - 2008.10.20

Keywords

Alcohols
Fluorination
Fluorine
Nucleophilic substitution
Tetrabutylammonium fluoride

Quacquarelli Symonds(QS) Subject Topics

Engineering - Petroleum
Engineering - Chemical
Chemistry

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10.1002/anie.200803150

Cite this

@article{b6d4f38c5c6f42158032a7d9e854fb73,

title = "Tetrabutylammonium tetra(tert-butyl alcohol)-coordinated fluoride as a facile fluoride source",

abstract = "(Figure Presented) F- on: The title compound TBAF(tBuOH) 4 can act as a highly effective fluoride source for nucleophilic fluorination thanks to its favorable properties, such as a stable structure (in which the fluoride ion is surrounded by four bulky nonpolar protic alcohol molecules), a dehydrated state, low hygroscopicity, good solubility in organic solvents, good nucleophilicity, and low basicity.",

keywords = "Alcohols, Fluorination, Fluorine, Nucleophilic substitution, Tetrabutylammonium fluoride",

author = "Kim, \{Dong Wook\} and Jeong, \{Hwan Jeong\} and Lim, \{Seok Tae\} and Sohn, \{Myung Hee\}",

year = "2008",

month = oct,

day = "20",

doi = "10.1002/anie.200803150",

language = "English",

volume = "47",

pages = "8404--8406",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

number = "44",

}

TY - JOUR

T1 - Tetrabutylammonium tetra(tert-butyl alcohol)-coordinated fluoride as a facile fluoride source

AU - Kim, Dong Wook

AU - Jeong, Hwan Jeong

AU - Lim, Seok Tae

AU - Sohn, Myung Hee

PY - 2008/10/20

Y1 - 2008/10/20

N2 - (Figure Presented) F- on: The title compound TBAF(tBuOH) 4 can act as a highly effective fluoride source for nucleophilic fluorination thanks to its favorable properties, such as a stable structure (in which the fluoride ion is surrounded by four bulky nonpolar protic alcohol molecules), a dehydrated state, low hygroscopicity, good solubility in organic solvents, good nucleophilicity, and low basicity.

AB - (Figure Presented) F- on: The title compound TBAF(tBuOH) 4 can act as a highly effective fluoride source for nucleophilic fluorination thanks to its favorable properties, such as a stable structure (in which the fluoride ion is surrounded by four bulky nonpolar protic alcohol molecules), a dehydrated state, low hygroscopicity, good solubility in organic solvents, good nucleophilicity, and low basicity.

KW - Alcohols

KW - Fluorination

KW - Fluorine

KW - Nucleophilic substitution

KW - Tetrabutylammonium fluoride

UR - https://www.scopus.com/pages/publications/54249102549

U2 - 10.1002/anie.200803150

DO - 10.1002/anie.200803150

M3 - Journal article

C2 - 18825757

AN - SCOPUS:54249102549

SN - 1433-7851

VL - 47

SP - 8404

EP - 8406

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 44

ER -

Tetrabutylammonium tetra(tert-butyl alcohol)-coordinated fluoride as a facile fluoride source

Abstract

Keywords

Quacquarelli Symonds(QS) Subject Topics

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