The function of Dmrt genes in vertebrate development: It is not just about sex

Chang Soo Hong; Byung Yong Park; Jean Pierre Saint-Jeannet

doi:10.1016/j.ydbio.2007.07.035

The function of Dmrt genes in vertebrate development: It is not just about sex

Chang Soo Hong
, Byung Yong Park
, Jean Pierre Saint-Jeannet^*

^*Corresponding author for this work

Department of Veterinary Medicine

University of Pennsylvania

Research output: Contribution to journal › Review article › peer-review

118 Scopus citations

Abstract

The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.

Original language	English
Pages (from-to)	1-9
Number of pages	9
Journal	Developmental Biology
Volume	310
Issue number	1
DOIs	https://doi.org/10.1016/j.ydbio.2007.07.035
State	Published - 2007.10.1

Keywords

DM domain
Dmrt
Gonads
Laterality
Nasal placode
Olfactory system
Sex determination
Somites

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10.1016/j.ydbio.2007.07.035

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title = "The function of Dmrt genes in vertebrate development: It is not just about sex",

abstract = "The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.",

keywords = "DM domain, Dmrt, Gonads, Laterality, Nasal placode, Olfactory system, Sex determination, Somites",

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T2 - It is not just about sex

AU - Hong, Chang Soo

AU - Park, Byung Yong

AU - Saint-Jeannet, Jean Pierre

PY - 2007/10/1

Y1 - 2007/10/1

N2 - The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.

AB - The Dmrt genes encode a large family of transcription factors whose function in sexual development has been well studied in invertebrates and vertebrates. Their expression pattern is not restricted to the developing gonads, indicating that Dmrt genes might regulate other developmental processes. Here we review the expression pattern of several members of this family across species and summarize recent findings on the function of a subset of these genes in non-gonadal tissues.

KW - DM domain

KW - Dmrt

KW - Gonads

KW - Laterality

KW - Nasal placode

KW - Olfactory system

KW - Sex determination

KW - Somites

UR - https://www.scopus.com/pages/publications/34548812861

U2 - 10.1016/j.ydbio.2007.07.035

DO - 10.1016/j.ydbio.2007.07.035

M3 - Review article

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AN - SCOPUS:34548812861

SN - 0012-1606

VL - 310

SP - 1

EP - 9

JO - Developmental Biology

JF - Developmental Biology

IS - 1

ER -

The function of Dmrt genes in vertebrate development: It is not just about sex

Abstract

Keywords

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