Three naphthalenes from root bark of Hibiscus syriacus

Ick Dong Yoo; Bong Sik Yun; In Kyoung Lee; In Ja Ryoo; Dong Ho Choung; Kyou Hoon Han

doi:10.1016/S0031-9422(97)00674-2

Three naphthalenes from root bark of Hibiscus syriacus

Ick Dong Yoo^*
, Bong Sik Yun
, In Kyoung Lee
, In Ja Ryoo
, Dong Ho Choung
, Kyou Hoon Han

^*Corresponding author for this work

Environmental Biotechnology

Korea Institute of Science and Technology

Research output: Contribution to journal › Journal article › peer-review

34 Scopus citations

Abstract

Three new naphthalenes, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. These compounds were identified as 2,7-dihydroxy-6-methyl-8-methoxy-l-naphthalenecarbaldehyde, 2-hydroxy-6- hydroxymethyl-7,8-dimethoxy-l-naphthalenecarbaldehyde, 1-carboxy-2,8- dihydroxy-6-methyl-7-methoxynaphthalenecarbolactone (1 → 8), respectively, on the basis of various spectral studies. The compounds inhibited lipid peroxidation with IC₅₀s of 0.54,5.90 and 1.02 μg ml^-1, respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED₅₀ of 1.5-2.4 μg ml^-1.

Original language	English
Pages (from-to)	799-802
Number of pages	4
Journal	Phytochemistry
Volume	47
Issue number	5
DOIs	https://doi.org/10.1016/S0031-9422(97)00674-2
State	Published - 1998.03

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Cytotoxicity
Hibiscus syriacus
Lipid peroxidation inhibitory activity
Maivaceae
Naph- thalenecarbaldehyde
Naphthalene
Naphthalenecarbolactone
Root bark
Syriacusins

Access to Document

10.1016/S0031-9422(97)00674-2

Cite this

@article{65c0c7ebcfff44259fc5fb434a2f50a2,

title = "Three naphthalenes from root bark of Hibiscus syriacus",

abstract = "Three new naphthalenes, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. These compounds were identified as 2,7-dihydroxy-6-methyl-8-methoxy-l-naphthalenecarbaldehyde, 2-hydroxy-6- hydroxymethyl-7,8-dimethoxy-l-naphthalenecarbaldehyde, 1-carboxy-2,8- dihydroxy-6-methyl-7-methoxynaphthalenecarbolactone (1 → 8), respectively, on the basis of various spectral studies. The compounds inhibited lipid peroxidation with IC50s of 0.54,5.90 and 1.02 μg ml-1, respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 μg ml-1.",

keywords = "Cytotoxicity, Hibiscus syriacus, Lipid peroxidation inhibitory activity, Maivaceae, Naph- thalenecarbaldehyde, Naphthalene, Naphthalenecarbolactone, Root bark, Syriacusins",

author = "Yoo, \{Ick Dong\} and Yun, \{Bong Sik\} and Lee, \{In Kyoung\} and Ryoo, \{In Ja\} and Choung, \{Dong Ho\} and Han, \{Kyou Hoon\}",

year = "1998",

month = mar,

doi = "10.1016/S0031-9422(97)00674-2",

language = "English",

volume = "47",

pages = "799--802",

journal = "Phytochemistry",

issn = "0031-9422",

number = "5",

}

TY - JOUR

T1 - Three naphthalenes from root bark of Hibiscus syriacus

AU - Yoo, Ick Dong

AU - Yun, Bong Sik

AU - Lee, In Kyoung

AU - Ryoo, In Ja

AU - Choung, Dong Ho

AU - Han, Kyou Hoon

PY - 1998/3

Y1 - 1998/3

N2 - Three new naphthalenes, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. These compounds were identified as 2,7-dihydroxy-6-methyl-8-methoxy-l-naphthalenecarbaldehyde, 2-hydroxy-6- hydroxymethyl-7,8-dimethoxy-l-naphthalenecarbaldehyde, 1-carboxy-2,8- dihydroxy-6-methyl-7-methoxynaphthalenecarbolactone (1 → 8), respectively, on the basis of various spectral studies. The compounds inhibited lipid peroxidation with IC50s of 0.54,5.90 and 1.02 μg ml-1, respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 μg ml-1.

AB - Three new naphthalenes, designated as syriacusins A-C, were isolated from the root bark of Hibiscus syriacus. These compounds were identified as 2,7-dihydroxy-6-methyl-8-methoxy-l-naphthalenecarbaldehyde, 2-hydroxy-6- hydroxymethyl-7,8-dimethoxy-l-naphthalenecarbaldehyde, 1-carboxy-2,8- dihydroxy-6-methyl-7-methoxynaphthalenecarbolactone (1 → 8), respectively, on the basis of various spectral studies. The compounds inhibited lipid peroxidation with IC50s of 0.54,5.90 and 1.02 μg ml-1, respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 μg ml-1.

KW - Cytotoxicity

KW - Hibiscus syriacus

KW - Lipid peroxidation inhibitory activity

KW - Maivaceae

KW - Naph- thalenecarbaldehyde

KW - Naphthalene

KW - Naphthalenecarbolactone

KW - Root bark

KW - Syriacusins

UR - https://www.scopus.com/pages/publications/0032032077

U2 - 10.1016/S0031-9422(97)00674-2

DO - 10.1016/S0031-9422(97)00674-2

M3 - Journal article

C2 - 9542172

AN - SCOPUS:0032032077

SN - 0031-9422

VL - 47

SP - 799

EP - 802

JO - Phytochemistry

JF - Phytochemistry

IS - 5

ER -

Three naphthalenes from root bark of Hibiscus syriacus

Abstract

UN SDGs

Keywords

Access to Document

Other files and links

Fingerprint

Cite this