Visible-light-mediated direct C3-arylation of 2: H -indazoles enabled by an electron-donor-acceptor complex

Kim Christopher C. Aganda; Junyoung Kim; Anna Lee

doi:10.1039/c9ob02074h

Visible-light-mediated direct C3-arylation of 2: H -indazoles enabled by an electron-donor-acceptor complex

Kim Christopher C. Aganda
, Junyoung Kim
, Anna Lee^*

^*Corresponding author for this work

Department of Chemistry

Myongji University

Research output: Contribution to journal › Journal article › peer-review

50 Scopus citations

Abstract

A mild visible-light-mediated, photocatalyst-free arylation of 2H-indazoles was developed. The formation of an electron donor-acceptor complex by 2H-indazoles and aryl diazonium salts in the presence of pyridine allows the direct arylation of 2H-indazoles under visible-light irradiation. This process provides an efficient route for the synthesis of C3-arylated-2H-indazoles, which are important scaffolds of various bioactive compounds.

Original language	English
Pages (from-to)	9698-9702
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	17
Issue number	45
DOIs	https://doi.org/10.1039/c9ob02074h
State	Published - 2019

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title = "Visible-light-mediated direct C3-arylation of 2: H -indazoles enabled by an electron-donor-acceptor complex",

abstract = "A mild visible-light-mediated, photocatalyst-free arylation of 2H-indazoles was developed. The formation of an electron donor-acceptor complex by 2H-indazoles and aryl diazonium salts in the presence of pyridine allows the direct arylation of 2H-indazoles under visible-light irradiation. This process provides an efficient route for the synthesis of C3-arylated-2H-indazoles, which are important scaffolds of various bioactive compounds.",

author = "Aganda, \{Kim Christopher C.\} and Junyoung Kim and Anna Lee",

note = "Publisher Copyright: {\textcopyright} 2019 The Royal Society of Chemistry.",

year = "2019",

doi = "10.1039/c9ob02074h",

language = "English",

volume = "17",

pages = "9698--9702",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

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TY - JOUR

T1 - Visible-light-mediated direct C3-arylation of 2

T2 - H -indazoles enabled by an electron-donor-acceptor complex

AU - Aganda, Kim Christopher C.

AU - Kim, Junyoung

AU - Lee, Anna

PY - 2019

Y1 - 2019

N2 - A mild visible-light-mediated, photocatalyst-free arylation of 2H-indazoles was developed. The formation of an electron donor-acceptor complex by 2H-indazoles and aryl diazonium salts in the presence of pyridine allows the direct arylation of 2H-indazoles under visible-light irradiation. This process provides an efficient route for the synthesis of C3-arylated-2H-indazoles, which are important scaffolds of various bioactive compounds.

AB - A mild visible-light-mediated, photocatalyst-free arylation of 2H-indazoles was developed. The formation of an electron donor-acceptor complex by 2H-indazoles and aryl diazonium salts in the presence of pyridine allows the direct arylation of 2H-indazoles under visible-light irradiation. This process provides an efficient route for the synthesis of C3-arylated-2H-indazoles, which are important scaffolds of various bioactive compounds.

UR - https://www.scopus.com/pages/publications/85075669992

U2 - 10.1039/c9ob02074h

DO - 10.1039/c9ob02074h

M3 - Journal article

C2 - 31696189

AN - SCOPUS:85075669992

SN - 1477-0520

VL - 17

SP - 9698

EP - 9702

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 45

ER -

Visible-light-mediated direct C3-arylation of 2: H -indazoles enabled by an electron-donor-acceptor complex

Abstract

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