Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha

Yun Woo Jang; In Kyoung Lee; Young Sook Kim; Sangku Lee; Ho Jae Lee; Seung Hun Yu; Bong Sik Yun

doi:10.1038/ja.2007.89

Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha

Yun Woo Jang
, In Kyoung Lee
, Young Sook Kim
, Sangku Lee
, Ho Jae Lee
, Seung Hun Yu
, Bong Sik Yun^*

^*Corresponding author for this work

Environmental Biotechnology

Korea Research Institute of Bioscience and Biotechnology
Chungnam National University

Research output: Contribution to journal › Journal article › peer-review

27 Scopus citations

Abstract

Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.

Original language	English
Pages (from-to)	696-699
Number of pages	4
Journal	Journal of Antibiotics
Volume	60
Issue number	11
DOIs	https://doi.org/10.1038/ja.2007.89
State	Published - 2007.11

Keywords

Antifungal activity
Mushroom
Polypropionate
Xylaria polymorpha
Xylarinic acid

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10.1038/ja.2007.89

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title = "Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha",

abstract = "Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.",

keywords = "Antifungal activity, Mushroom, Polypropionate, Xylaria polymorpha, Xylarinic acid",

author = "Jang, \{Yun Woo\} and Lee, \{In Kyoung\} and Kim, \{Young Sook\} and Sangku Lee and Lee, \{Ho Jae\} and Yu, \{Seung Hun\} and Yun, \{Bong Sik\}",

year = "2007",

month = nov,

doi = "10.1038/ja.2007.89",

language = "English",

volume = "60",

pages = "696--699",

journal = "Journal of Antibiotics",

issn = "0021-8820",

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TY - JOUR

T1 - Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha

AU - Jang, Yun Woo

AU - Lee, In Kyoung

AU - Kim, Young Sook

AU - Lee, Sangku

AU - Lee, Ho Jae

AU - Yu, Seung Hun

AU - Yun, Bong Sik

PY - 2007/11

Y1 - 2007/11

N2 - Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.

AB - Two new polypropionates designated as xylarinic acids A and B were isolated from the fruiting body of Xylaria polymorpha. Their structures were established as 4,6,8-trimethyl-2,4-decadienoic acid and 2,4,6-trimethyl-2-octenoic acid, respectively, on the basis of extensive spectroscopic analysis. Both compounds displayed significant antifungal activity against plant pathogenic fungi Pythium ultinum, Magnaporthe grisea, Aspergillus niger, Alternaria panax, and Fusarium oxysporium, whereas they did not show antibacterial and cytotoxic effect.

KW - Antifungal activity

KW - Mushroom

KW - Polypropionate

KW - Xylaria polymorpha

KW - Xylarinic acid

UR - https://www.scopus.com/pages/publications/40949093255

U2 - 10.1038/ja.2007.89

DO - 10.1038/ja.2007.89

M3 - Journal article

C2 - 18057699

AN - SCOPUS:40949093255

SN - 0021-8820

VL - 60

SP - 696

EP - 699

JO - Journal of Antibiotics

JF - Journal of Antibiotics

IS - 11

ER -

Xylarinic acids A and B, new antifungal polypropionates from the fruiting body of Xylaria polymorpha

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Keywords

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